Opened in 2014, Mission Hospital's Neuroscience & Spine Institute stands as the premier neurosurgical facility in Orange County


Mission Neuroscience Institute (MNI) is dedicated to assisting our patients and community in finding innovative therapies to help our patients better manage their healthcare through our research program. We share in the commitment and dedication to providing cutting edge therapy that can assist in managing our patients’ medical conditions today and possibly for a lifetime.

The MNI, has a highly experienced research team, consisting of physicians, nurses and certified clinical research coordinators, whose top priority is to conduct quality research aligned and harmonized with Good Clinical Practice standards. The physicians of the MNI herald from world-class academic institutions including The Johns Hopkins Hospital, Stanford University, Baylor University, University of Southern California, New York Medical College, and the University of California Los Angeles, providing subspecialized Centers of Excellence with the latest technological advances through innovative research.

Equipped with the latest surgical and intraoperative imaging equipment, our three large, 1,000 square foot operating rooms set the standard for clinical excellence. This provides our surgical teams with the latest technology at their fingertips, while providing the best possible care to patients through cutting edge medical device research.

To learn more about participating in one of a variety of clinical trials offered at Mission Neuroscience Institutes and the new cutting edge therapies that are available for helping patients return to fuller, better lives, contact us at or (949) 364-7723.